Perfluorooctanoic acid

1. Perfluorooctanoic acid is associated with stroke in humans.

   HumansP for trend < 0.01serum

   Revealing the Link Between Exposure to Per- and Polyfluoroalkyl Substances (PFAS) and Stroke: A Comprehensive Epidemiological and Network Toxicology Perspective · Cardiovascular toxicology · 13 Sep 2026

Stroke →

1. Perfluorooctanoic acid is associated with estimated pulse wave velocity in humans.

   Humansn = 5,209

   Associations of per- and polyfluoroalkyl substances (PFAS) exposure with arterial stiffness: Evidence from NHANES 2011-2018 · Ecotoxicology and environmental safety · 2 Sep 2026

Estimated pulse wave velocity →

1. Perfluorooctanoic acid raises the risk of pancreatic cancer in humans (HR 1.23 (1.05, 1.43)).

   Humans

   Mortality study of a PFOA-exposed cohort in the mid-Ohio Valley · Environment international · 30 Aug 2026

Pancreatic cancer →

1. Perfluorooctanoic acid is associated with bladder cancer in humans (HR 1.17 (0.98, 1.39)).

   Humans

   Mortality study of a PFOA-exposed cohort in the mid-Ohio Valley · Environment international · 30 Aug 2026

Bladder cancer →

1. Perfluorooctanoic acid raises the risk of brain cancer in humans (HR 1.25 (1.05, 1.50)).

   Humans

   Mortality study of a PFOA-exposed cohort in the mid-Ohio Valley · Environment international · 30 Aug 2026

Brain cancer →