Pembrolizumab
Pembrolizumab has been studied in 5 papers since 2020: 3 observational studies in people, 2 reviews; 1 in the past year. It is an approved medicine. The newest paper, Jan 29, 2026: “Drug-induced hyponatremia associated with sodium-glucose cotransporter 2 inhibitors, immune checkpoint inhibitors, and targeted anticancer agents”.
See all 5 papers on pembrolizumab
At a glance
2,190 trials, none about aging, 260 with no results posted.
- 2,190 trials, none about aging, 260 with no results posted
- 968 of 2,190 trials sponsored by its developers
- Humans3
Has pembrolizumab been tested in people?
0 of 2,190 about agingYes: 3 observational studies in people have been published, and 2,163 trials are registered.
Latest change Non-small cell lung cancer: Phase 3 → ApprovedNov 11, 2026
Approved
Sep 4, 2014Melanoma, Lung Cancer, Non-Small Cell, Unresectable or Metastatic Melanoma, nsclc, squamous nsclc, Classical Hodgkin Lymphoma, Head and Neck Squamous Cell Cancer, Malignant Pleural Mesothelioma, Primary Mediastinal Large B Cell Lymphoma, hnscc
Jul 17, 2015Melanoma, Hodgkin Disease, Carcinoma, Renal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Squamous Cell Carcinoma of Head and Neck, Urologic Neoplasms, Endometrial Neoplasms, Advanced Melanoma, Stage III Melanoma, non squamous non small cell lung carcinoma, Advanced Renal Cell Carcinoma, Biliary Cancer, Biliary Tract Carcinoma, Cervical Cancer, Classical Hodgkin Lymphoma, Colorectal Cancer, DMMR Colorectal Cancer, Endometrial Carcinoma, Head and Neck Squamous Cell Carcinoma, Locally Advanced Cervical Cancer, Locally Advanced Head and Neck Squamous Cell Carcinoma, Malignant Pleural Mesothelioma, Metastatic Colorectal Cancer, Metastatic Non-Small Cell Lung Carcinoma, Metastatic Non-Squamous Non-Small Cell Lung Carcinoma, Metastatic Squamous Non-Small Cell Lung Carcinoma, Metastatic Triple Negative Breast Cancer, Metastatic Urothelial Carcinoma, Mismatch Repair Deficient Colorectal Cancer, Oesophageal Carcinoma, Ovarian Cancer, Persistent, Recurrent, or Metastatic Cervical Cancer, Primary Peritoneal Carcinoma, Recurrent Endometrial Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma, Triple -Negative Breast Cancer, Urothelial Carcinoma, resectable muscle-invasive bladder cancer, locally advanced or metastatic urothelial carcinoma, recurrent or metastatic head and neck squamous cell carcinoma
Repurposing
Phase 4Recruiting157 trials
Phase 3Results posted59 trials
Phase 3Terminated18 trials
Phase 3Active, not recruiting31 trials
Phase 4Recruiting24 trials
Phase 3Recruiting2 trials
40 of 191Fewer
In trials
Autosomal Dominant Lewy Body Parkinson Disease 4
Phase 4Results posted162 trials
Ureteral Neoplasms
Phase 4Recruiting11 trials
Triple negative breast neoplasm
Phase 3Results posted135 trials
Prostatic neoplasm
Phase 3Results posted39 trials
Fallopian tube neoplasm
Phase 3Results posted30 trials
Adenocarcinoma Of Esophagus
Phase 3Completed18 trials
40 of 142Fewer
Readouts due
- Nov 20, 2026
- Nov 23, 2026
Study of XB010 in Subjects With Solid Tumors
Phase 1Recruiting
- Nov 30, 2026
Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer
Phase 2Active, not recruiting
- Dec 2026
Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors
Phase 2Active, not recruiting
- Dec 2026
Phase 2Active, not recruiting
- Dec 2026
40 of 126Fewer
Stopped
NCT03407170TerminatedAdvanced melanoma
Lack of Accrual
NCT04738487TerminatedLung neoplasm
Business Reasons
NCT03019588TerminatedStomach neoplasm
Business Reasons
NCT05092360TerminatedOvarian neoplasm
Study terminated due to business and strategic decision.
NCT04246177TerminatedHepatocellular carcinoma
Business Reasons
NCT04777851TerminatedHepatocellular carcinoma
The trial ended earlier than planned due to slow enrolment, which has made it unfeasible to achieve the target sample size within a reasonable timeframe. Consequently, a business decision has been made to discontinue funding for the trial.
40 of 68Fewer
Who is developing pembrolizumab?
3 companies: Merck Sharp & Dohme, NovoCure and Genmab.
Trial sponsors
Company216 trialsPhase 494,555 people
Company8 trialsPhase 4996 people
Company18 trialsPhase 35,848 people
Company16 trialsPhase 35,218 people
Company14 trialsPhase 34,192 people
Company13 trialsPhase 32,307 people
Company12 trialsPhase 31,716 people
Company11 trialsPhase 32,668 people