Nivolumab

FDA Opdivo

Dec 22, 2014Melanoma, Lung Cancer, Non-small Cell, METASTATIC NON-SMALL CELL LUNG CANCER, Recurrent Non Small Cell Lung Cancer, Resectable Non-Small Cell Lung Cancer, Stage IV Melanoma, Unresectable or Metastatic Melanoma, Carcinoma, Hepatocellular, Carcinoma, Renal Cell, Advanced Renal Cell Carcinoma, Advanced or Metastatic Esophageal Squamous Cell Carcinoma, Classical Hodgkin Lymphoma, Colorectal Cancer, Esophageal Adenocarcinoma, Esophageal Cancer, Gastric Cancer, Gastroesophageal Junction Cancer, Malignant Pleural Mesothelioma, Metastatic Colorectal Cancer, Metastatic Esophageal Squamous Cell Carcinoma, Metastatic Gastric Cancer, Metastatic Urothelial Carcinoma, Mismatch Repair Deficient Colorectal Cancer, Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck, Squamous Cell Carcinoma of the Head and Neck, Unresectable or Metastatic Hepatocellular Carcinoma, Urothelial Carcinoma, nsclc, locally advanced or metastatic urothelial carcinoma

FDA Opdivo

Mar 4, 2015

EMA Opdivo

Jun 19, 2015Melanoma, Hodgkin Disease, Carcinoma, Renal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Squamous Cell Carcinoma of Head and Neck, Urologic Neoplasms, Mesothelioma, Colorectal Neoplasms, Advanced Melanoma, Lung Cancer, Non-small Cell, METASTATIC NON-SMALL CELL LUNG CANCER, Resectable Non-Small Cell Lung Cancer, nsclc, Advanced or Metastatic Non-Small Cell Lung Cancer, Carcinoma, Hepatocellular, Advanced Hepatocellular Carcinoma, Advanced Renal Cell Carcinoma, Classical Hodgkin Lymphoma, Malignant Pleural Mesothelioma, Metastatic Colorectal Cancer, Metastatic Urothelial Carcinoma, Microsatellite Instability-High Colorectal Cancer, Muscle-invasive Urothelial Carcinoma, Squamous Cell Cancer of the Head and Neck, Urothelial Carcinoma, locally advanced or metastatic non small cell lung cancer

EMA Nivolumab BMS

Jul 20, 2015Withdrawn 2015Carcinoma, Non-Small-Cell Lung, Squamous Non-Small Cell Lung Cancer

Tumor

Phase 4Recruiting85 trials

Lung disease

Phase 4Terminated4 trials

Multiple myeloma

Phase 3Results posted20 trials

Glioblastoma

Phase 3Results posted28 trials

Solid tumor

Phase 4Recruiting12 trials

Lung adenocarcinoma

Phase 3Active, not recruiting5 trials

Thoracic Neoplasms

Phase 4Terminated2 trials

Prostatic neoplasm

Phase 3Results posted30 trials

Adenocarcinoma Of Esophagus

Phase 3Results posted13 trials

Fallopian tube neoplasm

Phase 3Active, not recruiting10 trials

Oropharyngeal Neoplasms

Phase 3Active, not recruiting7 trials

Ovarian epithelial carcinoma

Phase 3Active, not recruiting7 trials

NCT03138499TerminatedHodgkin lymphoma

Insufficient enrollment.

NCT05583188TerminatedLung neoplasm

Strategic

NCT04149574TerminatedBladder tumors

Insufficient enrollment, inability to meet protocol objectives, and slow accrual.

NCT04458909TerminatedNasopharyngeal carcinoma

External information

NCT03348904TerminatedAutosomal Dominant Lewy Body Parkinson Disease 4

Study halted prematurely and will not resume; participants are no longer being examined or receiving intervention.

NCT03906071TerminatedMetastatic non squamous non small cell lung cancer

Inability to meet protocol objectives