PAR1 agonist peptide

PAR1 agonist peptide has been studied in 1 paper since 2024: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Sep 2, 2024: “Cell sheet produced from periodontal ligament stem cells activated by PAR1 improves osteogenic differentiation”.

Intervention

1 paper studies it2 findingsUpdated

More peptides

  • 1 lab in 1 country
  • Funders: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior and 2 more
  • Cells1

What did studies of PAR1 agonist peptide find?

2

Studies of PAR1 agonist peptide measured 2 outcomes; the most studied are stem cell differentiation (1 study) and cellular senescence (1).

Stem cell differentiation

upin human cells1

1 study
  1. PAR1 agonist peptide improves stem cell differentiation in human cells.

    “Also, PAR1 activation decreased senescence and improved osteogenic differentiation of CSs by increasing mineralized nodule deposition and alkaline phosphatase concentration”

    Cellsin PDLSC cell sheets100 nM

    Cell sheet produced from periodontal ligament stem cells activated by PAR1 improves osteogenic differentiation

    Brazilian oral research

More on Stem cell differentiation

Cellular senescence

downin human cells1

1 study
  1. PAR1 agonist peptide decreases cellular senescence in human cells.

    “Also, PAR1 activation decreased senescence and improved osteogenic differentiation of CSs”

    Cellsin PDLSC cell sheets100 nM

    Cell sheet produced from periodontal ligament stem cells activated by PAR1 improves osteogenic differentiation

    Brazilian oral research

More on Cellular senescence

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