P7C3

1. P7C3 activates PI3K–AKT signalling in mice.

   Animalsagedextensor digitorum longus muscle10 mg/Kg body weight4 weeksmales

   Preliminary findings on the enhancement of skeletal muscle structure and function in aged male mice by P7C3 activation of nicotinamide phosphoribosyl transferase (NAMPT) · Experimental gerontology · 20 Sep 2026

PI3K–AKT signalling →

1. P7C3 increases NAMPT in mice.

   Animalsagedextensor digitorum longus muscle10 mg/Kg body weight4 weeksmales

   Preliminary findings on the enhancement of skeletal muscle structure and function in aged male mice by P7C3 activation of nicotinamide phosphoribosyl transferase (NAMPT) · Experimental gerontology · 20 Sep 2026

NAMPT →

1. P7C3 increases myofiber cross-sectional area in mice.

   Animalsagedtibialis anterior muscle10 mg/Kg body weight4 weeksmales

   Preliminary findings on the enhancement of skeletal muscle structure and function in aged male mice by P7C3 activation of nicotinamide phosphoribosyl transferase (NAMPT) · Experimental gerontology · 20 Sep 2026

1. P7C3 improves grip strength in mice.

   Animalsaged10 mg/Kg body weight4 weeksmales

   Preliminary findings on the enhancement of skeletal muscle structure and function in aged male mice by P7C3 activation of nicotinamide phosphoribosyl transferase (NAMPT) · Experimental gerontology · 20 Sep 2026

1. P7C3 improves muscle contractility in mice.

   Animalsagedskeletal muscle10 mg/Kg body weight4 weeksmales

   Preliminary findings on the enhancement of skeletal muscle structure and function in aged male mice by P7C3 activation of nicotinamide phosphoribosyl transferase (NAMPT) · Experimental gerontology · 20 Sep 2026