Old bone marrow-derived macrophage conditioned medium

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: National Science and Technology Council and 3 more

Cells1

Outcomes

CCL2

downin mouse cells1

1 study

Old bone marrow-derived macrophage conditioned medium decreases CCL2 in mouse cells.
“the old mouse BMDM secretome also suppressed hypoxia-induced cytokine expression (Il6, Ccl2) and EMT marker induction (Acta2, Fn1) in hypoxic TECs.”
Cellsin hypoxic renal tubular epithelial cells
Investigating the roles of macrophage age and circulating extracellular vesicles in cytoprotection of hypoxic renal tubular cell stress
BMC molecular and cell biology25 Mar 2026

Latest

1 in 12 months

BMC Molecular and Cell Biology26 Mar

Investigating the roles of macrophage age and circulating extracellular vesicles in cytoprotection of hypoxic renal tubular cell stress

Experiments in mouse cellsKidney

Paper

Old bone marrow-derived macrophage conditioned medium

Outcomes

Latest

Investigating the roles of macrophage age and circulating extracellular vesicles in cytoprotection of hypoxic renal tubular cell stress

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