1 paper3 findings
Growth differentiation factor 15
upin humans1
Obesity duration is associated with growth differentiation factor 15 in humans (+0.81% (95% CI, 0.25-1.36) per year beyond 25 years).
“0.81% (95% CI, 0.25-1.36) higher GDF-15”
Humansbeyond 25 years of obesity, fully adjusted model
More years of obesity linked to heart stress and injury markers
medRxiv11 Oct 2026Preprint
N-terminal pro-B-type natriuretic peptide
upin humans1
Obesity duration is associated with N-terminal pro-B-type natriuretic peptide in humans (+1.80% (95% CI, 0.54-3.06) per year beyond 25 years).
“each additional year of obesity beyond 25 years was associated with 1.80% (95% CI, 0.54-3.06) higher NT-proBNP”
Humansbeyond 25 years of obesity, fully adjusted model
More years of obesity linked to heart stress and injury markers
medRxiv11 Oct 2026Preprint
High-sensitivity cardiac troponin I
upin humans1
Obesity duration is associated with high-sensitivity cardiac troponin I in humans (+0.41% (95% CI, 0.07-0.76) per additional year).
“each additional year across the full range of obesity duration was associated with 0.41% (95% CI, 0.07-0.76) higher hs-cTnI.”
Humansfully adjusted model
More years of obesity linked to heart stress and injury markers
medRxiv11 Oct 2026Preprint
Each additional year of obesity was associated with 0.41% higher levels of a heart injury marker at age 62.Each additional year of obesity was associated with 0.41% higher levels of a heart injury marker at age 62.