AgingResearch.NewsJoin free

Novel oral nutritional supplement

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Human trial1

Outcomes

2

Oxidative phosphorylation

upin humans1

1 study

  1. Novel oral nutritional supplement activates oxidative phosphorylation in humans.

    “Gene sets related to mitochondrial functioning and oxidative phosphorylation were upregulated in the novel supplement group and downregulated in the standard supplement group.”

    Human trialwith (or at risk of) undernutrition12 weeksn = 82

    A novel oral nutritional supplement improves gait speed and mitochondrial functioning compared to standard care in older adults with (or at risk of) undernutrition: results from a randomized controlled trial

    Aging2 Apr 2021

More on Oxidative phosphorylation

Walking performance

upin humans1

1 study

  1. Novel oral nutritional supplement improves walking performance in humans.

    “The novel supplement group showed a larger improvement in walking performance on distances of 4m (treatment x time interaction P=0.048) and 400m (treatment x time interaction P=0.038) than the standard treatment group.”

    Human trialwith (or at risk of) undernutrition12 weeksn = 82

    A novel oral nutritional supplement improves gait speed and mitochondrial functioning compared to standard care in older adults with (or at risk of) undernutrition: results from a randomized controlled trial

    Aging2 Apr 2021

Latest

Related