NN501

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funders: Biotechnology and Biological Sciences Research Council and 1 more
  • 3 of 3 findings with company ties
  • Animals1

Outcomes

3

Fatty acid β-oxidation

upin mice1

1 study
  1. NN501 increases fatty acid β-oxidation in mice.

    “has a sustained effect on fatty-acid oxidation”

    Animalson treatment

    Analog of prolactin-releasing peptide reduces body weight primarily through sustained fatty acid oxidation rather than hypophagia

    Cell metabolism1 Dec 2025

More on Fatty acid β-oxidation

Energy expenditure

upin mice1

1 study
  1. NN501 increases energy expenditure in mice.

    “NN501 increases energy expenditure on treatment”

    Animalson treatment

    Analog of prolactin-releasing peptide reduces body weight primarily through sustained fatty acid oxidation rather than hypophagia

    Cell metabolism1 Dec 2025

Body weight

downin mice1

1 study
  1. NN501 decreases body weight in mice.

    “reduces body weight when administered systemically without causing obvious aversive responses”

    Animalssystemic administration

    Analog of prolactin-releasing peptide reduces body weight primarily through sustained fatty acid oxidation rather than hypophagia

    Cell metabolism1 Dec 2025

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