Naproxen

  • 2 independent labs in 3 countries
  • 10 trials, 2 about aging, 3 with no results posted
  • Funders: Canadian Institutes of Health Research and 1 more
  • Humans1
  • Animals1

Outcomes

1

Total choline

downin rats1

1 study
  1. Naproxen decreases total choline in rats.

    “Naproxen treatment altered neurochemistry in Tg animals only if administered beginning at 1 or 4 months of age, mitigating an otherwise observed increase in total choline”

    AnimalsTgF344-AD rat model of ADhippocampus

    Early treatment with naproxen alters hippocampal metabolites in the TgF344-AD rat model of Alzheimer's disease

    Neurochemistry internationalJul 20, 2026

More on Total choline

Associations

1

Lifespan

upin humans1

1 study
  1. Naproxen is associated with lifespan in humans.

    “Importantly, a few drugs were associated with increased lifespans, including notably Sildenafil, Atorvastatin, Naproxen and Estradiol.”

    Humans

    Association between prescription drugs and all-cause mortality risk in the UK population

    Aging cellOct 4, 2024

Trials

2 about aging, of 10

Trial sponsors

  • Viatris

    Company4 trialsPhase 425,473 people

  • Takeda

    Company2 trialsPhase 31,979 people

  • Pfizer

    Company1 trialPhase 3225 people

  • Bayer

    Company1 trialPhase 1117 people

  • AdventHealth

    1 trialPhase 4300 people

Latest

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