N-carbamoyl putrescine
N-carbamoyl putrescine has been studied in 1 paper since 2019: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Nov 3, 2019: “Is N-Carbamoyl Putrescine, the Decarboxylation Derivative of Citrulline, a Regulator of Muscle Protein Metabolism in Rats?”.
1 paper studies it5 findingsUpdated
See all 1 papers on N-carbamoyl putrescine
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Animals1
What did studies of N-carbamoyl putrescine find?
4Studies of N-carbamoyl putrescine measured 4 outcomes, among them fasted plasma glucose, MuRF1 expression and soleus muscle protein content.
Fasted plasma glucose
upin rats1
1 study
Fasted plasma glucose
upin rats1
N-carbamoyl putrescine increases fasted plasma glucose in rats during 4-day refeeding in malnourished old rats.
“this initial period of refeeding was also associated with elevated fasted plasma triglycerides and glucose, significant in NCP groups”
Animalsduring 4-day refeeding in malnourished old rats1 or 10 mg/kg/d4-day refeedingmales
Nutrients
MuRF1 expression
downin rats1
1 study
MuRF1 expression
downin rats1
N-carbamoyl putrescine decreases MuRF1 expression in rats during refeeding in malnourished old rats.
“The muscle RING-finger protein-1 expression was decreased in tibialis and urinary 3-methyl-histidine to creatinine ratio slightly lower with the supply of NCP.”
Animalsduring refeeding in malnourished old ratstibialis10 mg/kg/d4-day refeedingmales
Nutrients
Soleus muscle protein content
upin rats1
1 study
Soleus muscle protein content
upin rats1
N-carbamoyl putrescine increases soleus muscle protein content in healthy young rats.
“In healthy rats, muscle protein content was significantly increased in the soleus with NCP 5 mg/kg/d.”
Animalsin healthy young ratssoleus5 mg/kg/dtwo weeksmales
Nutrients
Weight gain and body composition
no changein rats1
1 study
Weight gain and body composition
no changein rats1
N-carbamoyl putrescine showed no clear effect on weight gain and body composition in healthy and malnourished old rats.
“NCP had no effect on weight gain and body composition in either of the two studies.”
Animalsin healthy and malnourished old ratsmales
Nutrients
What is N-carbamoyl putrescine linked with?
1Studies link N-carbamoyl putrescine with tibialis weight.
Tibialis weight
upin rats1
1 study
Tibialis weight
upin rats1
N-carbamoyl putrescine is associated with tibialis weight in malnourished old rats during refeeding.
“refeeding with NCP 10 mg/kg/d was associated with higher tibialis weight”
Animalsin malnourished old rats during refeedingtibialis10 mg/kg/d4-day refeedingmales
Nutrients