1 paper1 finding
Transcript isoform switching without changes in overall gene expression
upin mice1
Muscle mechanical overload induces transcript isoform switching without changes in overall gene expression in mice.
“A subset of genes showed significant isoform switching without corresponding changes in overall gene expression, suggesting post-transcriptional regulation in response to MOV.”
Animalsa subset of genesskeletal muscleacute
Older mouse muscle may switch less readily between RNA versions
Aging cell1 Oct 2026
Long-read RNA sequencing detected switching in 19 genes in overloaded adult mouse muscle, compared with none in overloaded aged muscle.Long-read RNA sequencing detected switching in 19 genes in overloaded adult mouse muscle, compared with none in overloaded aged muscle.