Mrna COVID-19 vaccine

Intervention

4 papers3 findings

  • 2 independent labs in 1 country
  • 1 trial, none about aging
  • Funder: Wellcome Trust
  • Humans3

Outcomes

2

Immune response

upin humans1

1 study
  1. Mrna COVID-19 vaccine improves immune response in humans.

    “mRNA COVID-19 vaccines generated strong immune responses in older adults, though lower than in younger groups.”

    Review

    Age-related changes in the immune system and challenges for the development of age-specific vaccines

    Annals of medicineMar 20, 2025

More on Immune response

SARS-CoV-2 neutralising antibodies

upin humans1

1 study
  1. Mrna COVID-19 vaccine increases SARS-CoV-2 neutralising antibodies in humans.

    “neutralising antibody responses were higher in Spikevax (Moderna) recipients, females, younger individuals and those with no underlying medical conditions”

    Humansafter two vaccine doses

    SARS-CoV-2 neutralising antibody activity in a highly vaccinated population: Longitudinal serology studies in Singapore

    medRxivMay 30, 2022Preprint

More on SARS-CoV-2 neutralising antibodies

Associations

1

Mortality

upin humans1

1 study
  1. Mrna COVID-19 vaccine is associated with mortality in humans.

    “Furthermore, multiple doses correlated with increased mortality; each additional dose led to earlier deaths and prolonged periods of elevated mortality.”

    Humans

    Citizen volunteers' disclosure request and web database for post-vaccination deaths among 4 million mRNA COVID-19 vaccine recipients in Japan: A massive wave of deaths occurring months after vaccination, amplified and prolonged by frequent dosing

    Zenodo (CERN European Organization for Nuclear Research)Feb 16, 2026Preprint

Trial sponsors

Latest

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