Moderate-intensity endurance training
Moderate-intensity endurance training has been studied in 2 papers since 2007: 1 trial in people, 1 in animals. The newest paper, Sep 27, 2025: “Exercise Improves Cardiac Dysfunction in D-Galactose-Treated Rats by Regulation of IGF-1-Humanin Pathway”.
2 papers study it4 findingsUpdated
“average HR during incremental exercise decreased significantly by 9 bpm (MOD, p < 0.05 vs. CO)”
None of its findings points the other way.
- 2 independent labs in 2 countries
- Funder: Kerman University of Medical Sciences
- Human trial1
- Animals1
Studies in people
1 study gave moderate-intensity endurance training to people and measured what changed.
down: Decreases heart rate-9 bpm (p < 0.05 vs. CO)
up: Increases VOp = 0.04 vs LOW
Randomized trial39 peopleBoth44 +/- 7 yrs12 weeks
Midlife adults
International journal of sports medicine, Jan 1, 2007
What did studies of Moderate-intensity endurance training find?
4Studies of Moderate-intensity endurance training measured 4 outcomes; the most studied are cardiac function (1 study), heart fibrosis (1) and VO (1).
Cardiac function
upin rats1
1 study
Cardiac function
upin rats1
Moderate-intensity endurance training improves cardiac function in rats.
“MIET and HIIT alleviated the changes in LVSP, ±maxdp/dt, CI, LVEDP, and Tau.”
Animalsin D-galactose-treated ratsheartmales
Journal of aging research
Heart fibrosis
downin rats1
1 study
Heart fibrosis
downin rats1
Moderate-intensity endurance training decreases heart fibrosis in rats.
“Histopathological score and heart fibrosis were reduced by HIIT and MIET in the D-gal group.”
Animalsin D-galactose-treated ratsheartmales
Journal of aging research
VO
upin humans1
1 study
VO
upin humans1
Moderate-intensity endurance training increases VO in humans (p = 0.04 vs LOW).
“for changes in oxygen uptake at the anaerobic threshold (VO (2AT)) it was observed that MOD was significantly more effective than CO (p = 0.048) and LOW (p = 0.04).”
Human trial12 weeksn = 39
Effectiveness of low-intensity endurance training
International journal of sports medicine
Heart rate
downin humans1
1 study
Heart rate
downin humans1
Moderate-intensity endurance training decreases heart rate in humans (-9 bpm (p < 0.05 vs. CO)).
“average HR during incremental exercise decreased significantly by 9 bpm (MOD, p < 0.05 vs. CO)”
Human trial12 weeksn = 39
Effectiveness of low-intensity endurance training
International journal of sports medicine