Mitochondrial division INHIBITOR-1
Intervention1 paper1 finding
- Animals1
Outcomes
1Cognitive impairment
no changein rats1Very low certainty
1 study
Cognitive impairment
no changein rats1Very low certainty
Mitochondrial division INHIBITOR-1 has no effect on cognitive impairment in rats.
“Additionally, MDV1 had no effect on mitochondrial function or cognitive outcomes.”
Animalsbrain1.2 mg/kg/day2 weeksfemales
The Myeloid Differentiation Factor‐2 Inhibitor Alleviates Brain Mitochondrial Oxidative Stress Without Improving Cognitive Impairment in Aged‐Female Rats · AAIC 2025 abstract · 23 Dec 2025