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Memantine + PHA-543613

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Nemzeti Kutatási, Fejlesztési és Innovaciós Alap
  • Animals1

Outcomes

1

Recognition memory

upin rats1

1 study

  1. Memantine + PHA-543613 improves recognition memory in rats.

    “Combination treatment of memantine and PHA-543613 successfully alleviated the age-related decline of recognition memory of rats by exceeding the effects of the corresponding monotreatments.”

    Animalsage-related decline

    Synergistic effects of memantine and alpha7 nicotinic acetylcholine receptor agonist PHA-543613 to improve memory of aged rats

    The international journal of neuropsychopharmacology22 Feb 2025

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