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Mechano growth factor E peptide

Mechano growth factor E peptide has been studied in 1 paper since 2011: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Feb 25, 2011: “Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in…”.

Intervention

1 paper studies it4 findingsUpdated

More peptides

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Cells1

What did studies of Mechano growth factor E peptide find?

4

Studies of Mechano growth factor E peptide measured 4 outcomes; the most studied are reserve cells percentage (1 study), muscle cell hypertrophy (1) and cellular senescence (1).

Reserve cells percentage

downin human cells1

1 study

  1. Mechano growth factor E peptide decreases reserve cells percentage in human cells.

    “significant decrease in the percentage of reserve cells was observed in all cultures.”

    Cellsskeletal muscle

    Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages

    Mechanisms of ageing and development

More on Reserve cells percentage

Muscle cell hypertrophy

upin human cells1

1 study

  1. Mechano growth factor E peptide increases muscle cell hypertrophy in human cells.

    “hypertrophy associated with a significant decrease in the percentage of reserve cells was observed in all cultures.”

    Cellsskeletal muscle

    Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages

    Mechanisms of ageing and development

Cellular senescence

downin human cells1

1 study

  1. Mechano growth factor E peptide decreases cellular senescence in human cells.

    “delays senescence of satellite cells isolated from neonatal and young adult but not from old adult muscle”

    Cellsskeletal muscle

    Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages

    Mechanisms of ageing and development

More on Cellular senescence

Proliferative lifespan

upin human cells1

1 study

  1. Mechano growth factor E peptide increases proliferative lifespan in human cells.

    “MGF-E peptide significantly increases the proliferative life span and delays senescence of satellite cells isolated from neonatal and young adult but not from old adult muscle”

    Cellsskeletal muscle

    Mechano Growth Factor E peptide (MGF-E), derived from an isoform of IGF-1, activates human muscle progenitor cells and induces an increase in their fusion potential at different ages

    Mechanisms of ageing and development

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