Maternal food restriction

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

3

GDF9

downin rats1

1 study
  1. Maternal food restriction decreases GDF9 in rats (P=0.0047 and P=0.0023).

    “MFR induced a significant decrease in Cyp17 and Gdf-9 gene expression in the offspring of both FRG1 and FRG2 females when compared with the controls (Cyp17: P=0.0018 and P=0.0016, respectively; Gdf-9: P=0.0047 and P=0.0023, respectively)”

    Animalsovaryfemales

    Intergenerational response of steroidogenesis-related genes to maternal malnutrition

    Journal of developmental origins of health and disease21 Feb 2019

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CYP17A1

downin rats1

1 study
  1. Maternal food restriction decreases CYP17A1 in rats (P=0.0018 and P=0.0016).

    “MFR induced a significant decrease in Cyp17 and Gdf-9 gene expression in the offspring of both FRG1 and FRG2 females when compared with the controls”

    Animalsovaryfemales

    Intergenerational response of steroidogenesis-related genes to maternal malnutrition

    Journal of developmental origins of health and disease21 Feb 2019

More on CYP17A1

CYP19A1

upin rats1

1 study
  1. Maternal food restriction increases CYP19A1 in rats.

    “At week 4, MFR significantly increased the expression of RNAs for all analyzed genes in both FRG1 and FRG2 females”

    Animalsovaryfemales

    Intergenerational response of steroidogenesis-related genes to maternal malnutrition

    Journal of developmental origins of health and disease21 Feb 2019

More on CYP19A1

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