Lyral
Intervention1 paper3 findingsPubChem 91604
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
Funders: Buck Institute for Research on Aging and 5 more
- Animals1
Outcomes
3Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Lyral decreases cellular senescence in human cells.
Cellsin human embryonic stem cell-derived myotubes
The ectopic olfactory receptor OR10J5 counteracts skeletal muscle senescence and age-related decline · Research Square · 21 Sep 2026 · Preprint
Physical function
upin mice1
1 study
Physical function
upin mice1
Lyral improves physical function in mice.
Animalsin naturally aged wild-type miceskeletal muscle
The ectopic olfactory receptor OR10J5 counteracts skeletal muscle senescence and age-related decline · Research Square · 21 Sep 2026 · Preprint
Muscle mass
upin mice1
1 study
Muscle mass
upin mice1
Lyral increases muscle mass in mice.
Animalsin naturally aged wild-type miceskeletal muscle
The ectopic olfactory receptor OR10J5 counteracts skeletal muscle senescence and age-related decline · Research Square · 21 Sep 2026 · Preprint