Lower education

4 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

3 independent labs in 3 countries

Humans4

Associations

Positive neurocognitive screening

upin humans1

1 study

Lower education is associated with positive neurocognitive screening in humans.
“Positive neurocognitive screening (57.8%) was associated with lower education, polypharmacy, and falls”
Humanspeople living with HIVn = 128
Brief Communication: Frailty and Neurocognitive Impairment in Older People Living with HIV: A Cross-Sectional Study from Southeastern Brazil
Research Square6 Oct 2026Preprint

More on Positive neurocognitive screening

Subjective cognitive decline

upin humans1OR 3.1

1 study

Lower education raises the risk of subjective cognitive decline in humans (OR 3.1, 95% CI = 2.2, 3.2).
“individuals without a college degree (OR 3.1, 95% CI = 2.2, 3.2), and those with low income (OR 2.7, 95% CI = 1.8, 2.5) were more likely to report SCD.”
Humans
The Social Determinants of Subjective Cognitive Decline among Adults Age 45 and Over: Implications for Action
GSA 2025 abstract31 Dec 2025

Dementia

upin humans1OR 1.45

1 study