Low pro-inflammatory diet
Intervention1 paper2 findings
- Humans1
Outcomes
2Heat temporal summation
downin humans1Very low certainty
1 study
Heat temporal summation
downin humans1Very low certainty
Low pro-inflammatory diet decreases heat temporal summation in humans (β = -22.028, FDR p = .049).
“Increased low pro-inflammatory diet decreased heat TS facilitation in the GrimAge-adjusted model (β = -22.028, SE = 8.270, raw p = .009, FDR p = .049).”
Humanschronic low back pain, adjusting for GrimAgen = 200
Joint Associations of Dietary Inflammatory Index and Epigenetic Aging with Central Sensitization in Chronic Low Back Pain: Latent Profile and Multiple Regression Analyses · Preprints.org · 3 Sep 2026 · Preprint
Conditioned pain modulation
upin humans1Very low certainty
1 study
Conditioned pain modulation
upin humans1Very low certainty
Low pro-inflammatory diet increases conditioned pain modulation in humans (β = 49.788, FDR p = .013).
“Increased low pro-inflammatory diet increased CPM only after accounting for DunedinPACE (β = 49.788, SE = 15.433, raw p = .002, FDR p = .013)”
Humanschronic low back pain, adjusting for DunedinPACEn = 200
Joint Associations of Dietary Inflammatory Index and Epigenetic Aging with Central Sensitization in Chronic Low Back Pain: Latent Profile and Multiple Regression Analyses · Preprints.org · 3 Sep 2026 · Preprint