Joint Associations of Dietary Inflammatory Index and Epigenetic Aging with Central Sensitization in Chronic Low Back Pain: Latent Profile and Multiple Regression Analyses
Preprints.org
Abstract
Nonspecific chronic low back pain (NSCLBP) is associated with central sensitization, and both diet quality and epigenetic aging are proposed modifiable, mechanistic contributors to this process. We examined how dietary profiles and epigenetic aging affect central sensitization in NSCLBP.
- Low pro-inflammatory diet
- DNA methylation
- Inflammation
- Central sensitization
- Chronic low back pain
- Humans
The paper
Fiona B A T Agbor, Peng Li, Brenda M. Bertrand, Edwin N. Aroke
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Ellen L. Smith, Khalid Walid Freij, Larissa J. Strath, Philemon Domoyeri, Kiari K. Davis, Asia M. Wiggins, Demario S. Overstreet, Tammie L. Quinn, Shivraj S. Grewal, Anushka Arora, Robert E. Sorge, Burel R. Goodin,Preprints.org · 3 Sep 2026 · CC BY · Preprint, not peer-reviewed

