Low oxygen

1 paper1 finding

1 lab in 2 countries

Funders: Alex's Lemonade Stand Foundation for Childhood Cancer and 7 more

Cells1

Outcomes

1

DNA methylation

no changein human cells1

1 study

Low oxygen has no effect on DNA methylation in human cells.
“Culture under low oxygen extended the life-span of TIG-7 cells but did not alter the rate of DNA demethylation.”
Cells3% O2 culture
Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts
Epigenetics3 Sep 2008

More on DNA methylation

Funding

1 grant since 2024

Defense Health AgencyUS$4.2m

Breathing low oxygen to enhance spinal stimulation training and functional recovery for aging adults with chronic sci: the bo2st-ii trial
Defense Health AgencySpaulding Rehabilitation HospitalUS$4.2m2024–2028

Latest

Epigenetics3 Sep

Stable knockdown of PASG enhances DNA demethylation but does not accelerate cellular senescence in TIG-7 human fibroblasts

Experiments in human cellsCellular senescence