Low-magnitude high-frequency vibration

Intervention

1 paper4 findings

  • 1 lab in 2 countries
  • Funders: National Key Research and Development Program of China and 1 more
  • Animals1

Outcomes

4

AChR clustering

upin mouse cells1

1 study
  1. Low-magnitude high-frequency vibration increases AChR clustering in mouse cells.

    “In vitro, LMHFV could promote AChRs clustering in myotubes by increasing Dok7 expression through suppressing ERK1/2 phosphorylation.”

    Cellsmyotubes

    Prevention of age-related neuromuscular junction degeneration in sarcopenia by low-magnitude high-frequency vibration

    Aging cell27 Mar 2024

More on AChR clustering

DOK7

upin mice1

1 study
  1. Low-magnitude high-frequency vibration increases DOK7 in mice.

    “LMHFV increased Dok7 expression at Month 4 posttreatment.”

    Animalsposttreatment4 months

    Prevention of age-related neuromuscular junction degeneration in sarcopenia by low-magnitude high-frequency vibration

    Aging cell27 Mar 2024

More on DOK7

Neuromuscular junction morphological degeneration

downin mice1

1 study
  1. Low-magnitude high-frequency vibration decreases neuromuscular junction morphological degeneration in mice.

    “Vibration group presented improved NMJ function at Months 2 and 6 posttreatment, accompanied with alleviated morphological degeneration at Month 4 posttreatment.”

    Animalsposttreatment4 months

    Prevention of age-related neuromuscular junction degeneration in sarcopenia by low-magnitude high-frequency vibration

    Aging cell27 Mar 2024

Physical function

upin mice1

1 study
  1. Low-magnitude high-frequency vibration improves physical function in mice.

    “Skeletal muscle performance was improved at Month 4 post-LMHFV treatment.”

    Animalspost-LMHFV treatment4 months

    Prevention of age-related neuromuscular junction degeneration in sarcopenia by low-magnitude high-frequency vibration

    Aging cell27 Mar 2024

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