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Leucine depletion

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 3 more
  • Humans1

Outcomes

1

Cellular senescence

downin cells1

1 study

  1. Leucine depletion decreases cellular senescence in cells.

    “Depletion of leucine, one of the branched-chain amino acids, from cultured media decreased senescence”

    Cellsin cultured media

    TNFSF14⁺ natural killer cells prevent spontaneous abortion by restricting leucine-mediated decidual stromal cell senescence

    The EMBO journalSep 11, 2024

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