KRN5

1 paper3 findings

1 lab in 1 country

Funder: National Natural Science Foundation of China

Animals1

Outcomes

3

Apoptosis

upin mouse cells1

1 study

KRN5 induces apoptosis in mouse cells.
“Consequently, KRN5 effectively re-sensitizing senescent VSMCs to apoptosis.”
Cellsvascular smooth muscle cell
Targeting NFAT5 attenuates high sodium-induced vascular aging by re-sensitizing senescent smooth muscle cells to apoptosis
Cellular signalling4 Jun 2026

More on Apoptosis

Senescence-associated secretory phenotype (SASP)

downin mice1

1 study

KRN5 inhibits senescence-associated secretory phenotype (SASP) in mice.
“KRN5 significantly attenuated these aging phenotypes and suppressed the senescence-associated secretory phenotype (SASP) in vivo.”
Animalsin high-sodium diet-fed mice
Targeting NFAT5 attenuates high sodium-induced vascular aging by re-sensitizing senescent smooth muscle cells to apoptosis
Cellular signalling4 Jun 2026

More on Senescence-associated secretory phenotype (SASP)

Vascular aging

downin mice1

1 study

KRN5 decreases vascular aging in mice.
“KRN5 significantly attenuated these aging phenotypes and suppressed the senescence-associated secretory phenotype (SASP) in vivo.”
Animalsin high-sodium diet-fed mice
Targeting NFAT5 attenuates high sodium-induced vascular aging by re-sensitizing senescent smooth muscle cells to apoptosis
Cellular signalling4 Jun 2026

Latest

1 in 12 months

Cellular Signalling6 Jun

Targeting NFAT5 attenuates high sodium-induced vascular aging by re-sensitizing senescent smooth muscle cells to apoptosis

Experiments in miceApoptosis