Kainic acid

  • 2 independent labs in 2 countries
  • Funder: Tays
  • Animals2
  • Cells1

Outcomes

2

Taurine release

upin mice1

1 study
  1. Kainic acid increases taurine release in mice.

    “N-methyl-D-aspartate (NMDA), kainate and 2-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) potentiated taurine release concentration-dependently at each age”

    Animalshippocampus

    Taurine release from the developing and ageing hippocampus: stimulation by agonists of ionotropic glutamate receptors

    Mechanisms of ageing and development30 Dec 1997

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Gonadotropin-releasing hormone

upin rats1

1 study
  1. Kainic acid increases gonadotropin-releasing hormone in rats.

    “kainate appeared more efficacious in young and old rats, respectively.”

    Animalshypothalamic explantshypothalamusmales

    Different responses of gonadotropin-releasing hormone (GnRH) release to glutamate receptor agonists during aging

    Brain research bulletin1 Jan 1996

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