Iron supplementation
Iron supplementation has been studied in 6 papers since 2020: 2 observational studies in people, 1 in cells, 3 reviews; 4 in the past year. The newest paper, Sep 4, 2026: “Potential Health Consequences of Regular Blood Donation: Current Evidence and Remaining Uncertainties”.
6 papers study it3 findingsUpdated
See all 6 papers on iron supplementation
At a glance
The findings reach people, from one lab or study. 3 independent labs in 2 countries.
“iron supplementation was significantly associated with higher parkinsonism risk”
None of its findings points the other way.
- 3 independent labs in 2 countries
- Funders: American Federation for Aging Research and others
- Humans2
- Cells1
What did studies of iron supplementation find?
2Studies of iron supplementation measured 2 outcomes: cognitive function and age-related mitochondrial decline.
Cognitive function
upin humans1
1 study
Cognitive function
upin humans1
Iron supplementation improves cognitive function in humans (especially in the presence of anemia).
“In children, iron supplementation significantly improved cognitive performance, especially in the presence of anemia.”
Reviewespecially in the presence of anemia
Revista fisio&terapia.
Age-related mitochondrial decline
downin yeast cells1
1 study
Age-related mitochondrial decline
downin yeast cells1
Iron supplementation prevents age-related mitochondrial decline in yeast cells (vacuole-impaired cells and aging).
“Cysteine depletion or iron supplementation restores mitochondrial health in vacuole-impaired cells and prevents mitochondrial decline during aging”
Cellsvacuole-impaired cells and aging
Cysteine Toxicity Drives Age-Related Mitochondrial Decline by Altering Iron Homeostasis
Cell
What is iron supplementation linked with?
1Studies link iron supplementation with parkinsonism.
Parkinsonism
upin humans1
1 study
Parkinsonism
upin humans1
Iron supplementation is associated with parkinsonism in humans (British adults).
“iron supplementation was significantly associated with higher parkinsonism risk”
HumansBritish adultsn = 385,898
Nutrients