Iridoid glycosides from verbascum nigrum ssp. abietinum

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • Funders: European Regional Development Fund and 2 more
  • Model organisms1

Outcomes

3

hsf-1

upin worms1

1 study
  1. Iridoid glycosides from verbascum nigrum ssp. abietinum increases hsf-1 in worms.

    “Additionally, sgk-1/SGK-1, hsf-1/HSF1, and tcer-1/TCERG1 were consistently overexpressed”

    Model organisms

    Stress endurance mediates the healthspan-promoting effect of two newly described iridoid glycosides from Verbascum nigrum ssp. abietinum in Caenorhabditis elegans

    Phytomedicine : international journal of phytotherapy and phytopharmacology9 Feb 2026

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sek-1

upin worms1

1 study
  1. Iridoid glycosides from verbascum nigrum ssp. abietinum increases sek-1 in worms.

    “Both compounds upregulated sek-1/p38 (MAPK) and sqst-1/p62 (SQSTM1), indicating enhanced autophagy and stress response.”

    Model organisms

    Stress endurance mediates the healthspan-promoting effect of two newly described iridoid glycosides from Verbascum nigrum ssp. abietinum in Caenorhabditis elegans

    Phytomedicine : international journal of phytotherapy and phytopharmacology9 Feb 2026

More on sek-1

Healthspan

upin worms1

1 study
  1. Iridoid glycosides from verbascum nigrum ssp. abietinum improves healthspan in worms.

    “iridoid glycosides 1 and 2 from V. nigrum ssp. abietinum promote C. elegans healthspan”

    Model organisms

    Stress endurance mediates the healthspan-promoting effect of two newly described iridoid glycosides from Verbascum nigrum ssp. abietinum in Caenorhabditis elegans

    Phytomedicine : international journal of phytotherapy and phytopharmacology9 Feb 2026

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