IRF1-OVEREXPRESSING bone marrow mesenchymal stem cells

IRF1-OVEREXPRESSING bone marrow mesenchymal stem cells decrease bone marrow adiposity in mice.

Animalsin OVX and aged osteoporotic micebone marrow

Interferon Regulatory Factor 1 Inhibits the Adipogenic Differentiation of BMSCs via the AMPK-mTOR Signaling Axis and Induces Their Autophagy to Alleviate Osteoporosis-Related Bone Marrow Adiposity · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 17 Sep 2026