Intestinal epithelial stem cell transplant

Intestinal epithelial stem cell transplant has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Oct 31, 2022: “Intestinal epithelial stem cell transplants as a novel therapy for cerebrovascular stroke”.

Intervention

1 paper studies it4 findingsUpdated

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: American Heart Association and 3 more
  • Animals1

What did studies of Intestinal epithelial stem cell transplant find?

4

Studies of Intestinal epithelial stem cell transplant measured 4 outcomes; the most studied are cognitive-affective function (1 study), sensory-motor disability (1) and IL-17A (1).

Cognitive-affective function

upin rats1

1 study
  1. Intestinal epithelial stem cell transplant improves cognitive-affective function in rats.

    “improved stroke-induced acute (4d) sensory-motor disability and chronic (30d) cognitive-affective function”

    Animalsin older rats after stroke30d

    Intestinal epithelial stem cell transplants as a novel therapy for cerebrovascular stroke

    Brain, behavior, and immunity

Sensory-motor disability

downin rats1

1 study
  1. Intestinal epithelial stem cell transplant decreases sensory-motor disability in rats.

    “IESC transplants also improved stroke-induced acute (4d) sensory-motor disability”

    Animalsin older rats after stroke4d

    Intestinal epithelial stem cell transplants as a novel therapy for cerebrovascular stroke

    Brain, behavior, and immunity

IL-17A

downin rats1

1 study
  1. Intestinal epithelial stem cell transplant decreases IL-17A in rats.

    “reduced circulating levels of endotoxin LPS and the inflammatory cytokine IL-17A”

    Animalsin older rats after stroke

    Intestinal epithelial stem cell transplants as a novel therapy for cerebrovascular stroke

    Brain, behavior, and immunity

More on IL-17A

Gut permeability

downin rats1

1 study
  1. Intestinal epithelial stem cell transplant decreases gut permeability in rats.

    “decreased gut permeability”

    Animalsin older rats after stroke

    Intestinal epithelial stem cell transplants as a novel therapy for cerebrovascular stroke

    Brain, behavior, and immunity

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