INTERLEUKIN-15 + thymosin alpha 1
1 paper4 findings
- 1 lab
- Animals1
Outcomes
4PI3K–AKT signalling
downin mice1
1 study
PI3K–AKT signalling
downin mice1
INTERLEUKIN-15 + thymosin alpha 1 inhibits PI3K–AKT signalling in mice.
“combination attenuated chronically overactivated phosphatidylinositol 3-kinase/protein kinase B signaling in hepatic CD8+ T cells.”
Animalsorthotopic HCC modelcombination therapyhepatic CD8+ T cells
Journal of gastroenterology and hepatology26 Mar 2026
Senescent CD8+ T cells
downin mice1
1 study
Senescent CD8+ T cells
downin mice1
INTERLEUKIN-15 + thymosin alpha 1 decreases senescent CD8+ T cells in mice.
“It reduced the proportion of senescent CD8+ T cells while expanding activated effector populations”
Animalsorthotopic HCC modelcombination therapyliver
Journal of gastroenterology and hepatology26 Mar 2026
Survival
upin mice1
1 study
Survival
upin mice1
INTERLEUKIN-15 + thymosin alpha 1 extends lifespan survival in mice.
“The combination therapy significantly suppressed tumor growth and prolonged survival.”
Animalsorthotopic HCC modelcombination therapy
Journal of gastroenterology and hepatology26 Mar 2026
Tumor growth
downin mice1
1 study
Tumor growth
downin mice1
INTERLEUKIN-15 + thymosin alpha 1 decreases tumor growth in mice.
“The combination therapy significantly suppressed tumor growth and prolonged survival.”
Animalsorthotopic HCC modelcombination therapy
Journal of gastroenterology and hepatology26 Mar 2026