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Injectable prevascularized adipose tissue

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Japan Agency for Medical Research and Development and 1 more
  • 2 of 2 findings with company ties
  • Animals1

Outcomes

2

Angiogenesis

upin mice1

1 study

  1. Injectable prevascularized adipose tissue increases angiogenesis in mice (up to 1.6-fold increase).

    “This higher survival can be explained by the greater amount of blood vessels found (up to 1.6-fold increase)”

    Animalssubcutaneous adipose tissue3 months

    Injectable Prevascularized Mature Adipose Tissues (iPAT) to Achieve Long-Term Survival in Soft Tissue Regeneration

    Advanced healthcare materials28 Sep 2022

More on Angiogenesis

Graft volume maintenance

upin mice1

1 study

  1. Injectable prevascularized adipose tissue improves graft volume maintenance in mice (up to twice heavier, 84% ± 6% viability).

    “higher cell survival (84% ± 6% viability) and volume maintenance after 3 months (up to twice heavier) when compared to non-prevascularized balls and liposuctioned fat implanted controls”

    Animalssubcutaneous adipose tissue3 months

    Injectable Prevascularized Mature Adipose Tissues (iPAT) to Achieve Long-Term Survival in Soft Tissue Regeneration

    Advanced healthcare materials28 Sep 2022

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