IL-1ALPHA neutralising antibody

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 2 more
  • Animals1

Outcomes

1

Hepatic ischaemia-reperfusion injury

downin mice1

1 study
  1. IL-1ALPHA neutralising antibody decreases hepatic ischaemia-reperfusion injury in mice.

    “neutralising IL-1α effectively alleviated HIRI in aged livers”

    Animalsaged liversliver

    Crosstalk between liver sinusoidal endothelial cells and hepatocytes via IL-1α-IL1R1 axis exacerbates ischaemia/reperfusion injury in aged livers

    Gut9 Oct 2025

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