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IL-1 signaling inhibitor

IL-1 signaling inhibitor has been studied in 1 paper since 2023: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Jan 17, 2023: “Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing”.

Intervention

1 paper studies it1 findingUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: American Heart Association and others
  • Animals1

What did studies of IL-1 signaling inhibitor find?

1

Studies of IL-1 signaling inhibitor measured 1 outcome; the most studied are hematopoietic stem cell dysfunction (1 study).

Hematopoietic stem cell dysfunction

downin mice1

1 study

  1. IL-1 signaling inhibitor decreases hematopoietic stem cell dysfunction in mice.

    “Notably, niche deterioration, HSC dysfunction and defective regeneration can all be ameliorated by blocking IL-1 signalling.”

    Animalsduring ageing

    Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing

    Nature cell biology

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