Hypobaric pressure
1 paper4 findings
- 1 lab in 1 country
- Funders: Guangdong Provincial Pearl River Talents Program and 2 more
- Animals1
Outcomes
4Osteoporosis
downin mice1
1 study
Osteoporosis
downin mice1
Hypobaric pressure protects against osteoporosis in mice.
“rescue the osteoporosis phenotype in aged mice”
Animals
Nature biomedical engineering14 Jan 2026
Lifespan
upin mice1
1 study
Lifespan
upin mice1
Hypobaric pressure extends lifespan in mice.
“intermittent HP treatment can substantially extend the lifespan and rescue the osteoporosis phenotype in aged mice”
Animals
Nature biomedical engineering14 Jan 2026
Senescence-associated secretory phenotype (SASP)
downin mouse cells1
1 study
Senescence-associated secretory phenotype (SASP)
downin mouse cells1
Hypobaric pressure decreases senescence-associated secretory phenotype (SASP) in mouse cells.
“intermittent HP treatment to specifically induce senescent cells to undergo LDCD and reduce the senescence-associated secretory phenotype”
Cellssenescent cells
Nature biomedical engineering14 Jan 2026
Lysosome-dependent cell death
upin mouse cells1
1 study
Lysosome-dependent cell death
upin mouse cells1
Hypobaric pressure induces lysosome-dependent cell death in mouse cells.
“hypobaric pressure (HP) at -375 mmHg without hypoxia induces cells to undergo lysosome-dependent cell death (LDCD)”
Cells
Nature biomedical engineering14 Jan 2026
Latest
1 in 12 monthsNature Biomedical Engineering
Intermittent hypobaric pressure induces selective senescent cell death and alleviates age-related osteoporosis
Experiments in miceOsteoporosis