Human neural progenitor cells expressing IGF-1

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Animals1

Outcomes

1

Loss of motor neurons

downin mice1

1 study
  1. Human neural progenitor cells expressing IGF-1 decreases loss of motor neurons in mice.

    “Transplantation of GDNF- or IGF-1-expressing hNPs attenuated the loss of motor neurons”

    AnimalsSOD1(G93A) transgenic micespinal cord

    Growth factor-expressing human neural progenitor cell grafts protect motor neurons but do not ameliorate motor performance and survival in ALS mice

    Experimental & molecular medicine31 Jul 2009

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