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Human follicular fluid-derived exosomes

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Natural Science Foundation of Guangdong Province and 4 more
  • Humans1

Outcomes

2

PI3K–AKT signalling

upin mice1

1 study

  1. Human follicular fluid-derived exosomes activate PI3K–AKT signalling in mice.

    “Furthermore, the PI3K/AKT signaling pathway, which is known to be related to folliculogenesis, was activated by the application of exosomes in aging female mice.”

    Animalsin aging female micefemales

    Proteomic Analysis of Human Follicular Fluid-Derived Exosomes Reveals That Insufficient Folliculogenesis in Aging Women is Associated With Infertility

    Molecular & cellular proteomics : MCP28 Feb 2025

More on PI3K–AKT signalling

Follicular maturation

upin mice1

1 study

  1. Human follicular fluid-derived exosomes improve follicular maturation in mice.

    “the application of exosomes, particularly those derived from young female group, facilitated the successful maturation of follicles.”

    Animalsin aging female micefemales

    Proteomic Analysis of Human Follicular Fluid-Derived Exosomes Reveals That Insufficient Folliculogenesis in Aging Women is Associated With Infertility

    Molecular & cellular proteomics : MCP28 Feb 2025

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