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Hnrnpdl gene therapy

Hnrnpdl gene therapy has been studied in 1 paper since 2021: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Sep 22, 2021: “Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing”.

Intervention

1 paper studies it1 findingUpdated

See all 1

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Chinese Academy of Sciences and 2 more
  • Animals1

What did studies of Hnrnpdl gene therapy find?

1

Studies of Hnrnpdl gene therapy measured 1 outcome; the most studied are cognitive function (1 study).

Cognitive function

upin mice1

1 study

  1. Hnrnpdl gene therapy improves cognitive function in APP/PS1 mice.

    “overexpression of L-DL improves cognitive function in AD mice”

    Animalsin APP/PS1 miceAAV-mediated transductionbrain

    Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing

    Molecular neurodegeneration

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