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HMGB1 box a

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

1

Aging features

upin cells1upin rats1

1 study

  1. HMGB1 box a improves aging features in cells.

    “Increased gaps consolidated DNA durability, leading to DNA protection and improved aging features in senescent cells and two aging rat models similar to those of young organisms.”

    Cells

    The roles of HMGB1-produced DNA gaps in DNA protection and aging biomarker reversal

    FASEB bioAdvancesMar 28, 2022

  2. HMGB1 box a improves aging features in rats.

    “Increased gaps consolidated DNA durability, leading to DNA protection and improved aging features in senescent cells and two aging rat models similar to those of young organisms.”

    Animals

    The roles of HMGB1-produced DNA gaps in DNA protection and aging biomarker reversal

    FASEB bioAdvancesMar 28, 2022

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