High-intensity functional exercise

High-intensity functional exercise has been studied in 11 papers since 2016: 6 trials in people, 2 reviews; 3 in the past year. The newest paper, Sep 28, 2026: “INTERVENTIONS TO PREVENT FALLS AND FRACTURES IN NURSING HOMES: A SYSTEMIC LITERATURE REVIEW”.

Intervention

11 papers study it14 findingsUpdated

See all 11 papers on high-intensity functional exercise

At a glance

The findings reach people, from one lab or study. 4 independent labs in 4 countries.

“There was no difference between groups for the improvement in EMS from admission to discharge (effect size -0.07, 95% confidence interval: -0.26 to 0.11, P = 0.446)”
The effects of a high-intensity functional exercise group on clinical outcomes in hospitalised older adults: an assessor-blinded, randomised-controlled trialAge and ageing2016doi:10.1093/ageing/afw215

1 of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 4 independent labs in 4 countries
  • 1 finding against
  • Funders: Vetenskapsrådet and 7 more
  • Human trial6

Studies in people

5 studies gave high-intensity functional exercise to people and measured what changed.

What changedDesignPeopleSource

up: Improves physical functionp < 0.05, d = 1.97

up: Improves dual-task performancep < 0.05, d = 2.36 (sit-to-stand), d = 2.76 (walk)

down: Decreases menopausal symptomsp < 0.05

Randomized trial8 weeks40 peopleWomen50-65Postmenopausal women; postmenopausalBMC women's health, Jun 1, 2026

no change: Has no effect on backward walking speedtest 1) 0.005 m/s, P = .788 and -0.006 m/s, P = .754 and test 2) 0.030 m/s, P = .231 and 0.015 m/s, P = .569

up: Improves backward walking speed0.094 m/s, P = .027

Randomized trial4 and 7 monthsBothmean 85 yearsThe oldest old; in people with dementia living in nursing homesGait & posture, Jan 13, 2021

no change: Has no effect on cognitive functionMMSE -0.27 (95% CI -1.4 to 0.87, p = 0.644) at 4 months; -1.15 (95% CI -2.32 to 0.03) at 7 months

no change: Has no effect on executive functionVF -0.53 (95% CI -1.42 to 0.35, p = 0.241) at 4 months; -0.18 (95% CI -1.09 to 0.74) at 7 months

Randomized trial4 months141 peopleBothmean age of 85 yOlder adults; people with dementia living in nursing homesJournal of Alzheimer's disease : JAD, Jan 1, 2017

no change: Has no effect on mobilityeffect size -0.07, 95% CI -0.26 to 0.11, P = 0.446

no change: Has no effect on discharge destinationP = 0.904

down: Decreases therapist treatment time31-205 min/week saved

Randomized trialthree times a week468 peopleBothmean 84.3 yearsOlder adults; group programme combined with individual physiotherapy versus individual physiotherapy aloneAge and ageing, Dec 10, 2016

up: Improves balanceBBS 4.2, 95% CI 1.8 to 6.6

up: Improves activities of daily living independence and balance

Randomized trial4 months186 people65 and olderOlder adults; older adults with dementia in residential careJournal of the American Geriatrics Society, Jan 1, 2016

What did studies of high-intensity functional exercise find?

12

Studies of high-intensity functional exercise measured 12 outcomes; the most studied are backward walking speed (1 study), urogenital symptoms (1) and menopausal symptoms (1).

Backward walking speed

upin humans1no changein humans1

1 study
  1. High-intensity functional exercise improves backward walking speed in participants who habitually walked unaided, interaction at 7 months (0.094 m/s, P = .027).

    “exercise effects differed significantly between participants who habitually walked unaided compared with those that used a walking aid at 7 months (0.094 m/s, P = .027)”

    Human trialin participants who habitually walked unaided, interaction at 7 months7 months

    Exercise effects on backward walking speed in people with dementia: A randomized controlled trial

    Gait & posture

  2. High-intensity functional exercise showed no clear effect on backward walking speed in people with dementia living in nursing homes (test 1) 0.005 m/s, P = .788 and -0.006 m/s, P = .754 and test 2) 0.030 m/s, P = .231 and 0.015 m/s, P = .569).

    “Linear mixed models showed no between-group effect in either backward walking speed test at 4 or 7 months”

    Human trialin people with dementia living in nursing homes4 and 7 months

    Exercise effects on backward walking speed in people with dementia: A randomized controlled trial

    Gait & posture

Urogenital symptoms

no changein humans1

1 study
  1. High-intensity functional exercise showed no clear effect on urogenital symptoms in humans (postmenopausal) (p > 0.05).

    “No significant differences were observed between the groups in SPPB balance, MRS urogenital symptoms, or MSQOL sexual problems (p > 0.05).”

    Human trialpostmenopausal8 weeksfemalesn = 40

    Effects of a high-intensity functional exercise program on menopausal symptoms, physical performance, and dual-task performance in postmenopausal women: a randomized controlled trial

    BMC women's health

Menopausal symptoms

downin humans1

1 study
  1. High-intensity functional exercise decreases menopausal symptoms in humans (postmenopausal) (p < 0.05).

    “Significant improvements were also observed in somatic and psychological subparameters and total MRS scores, as well as in all MSQOL subparameters except sexual problems (p < 0.05).”

    Human trialpostmenopausal8 weeksfemalesn = 40

    Effects of a high-intensity functional exercise program on menopausal symptoms, physical performance, and dual-task performance in postmenopausal women: a randomized controlled trial

    BMC women's health

More on Menopausal symptoms

Dual-task performance

upin humans1

1 study
  1. High-intensity functional exercise improves dual-task performance in humans (postmenopausal) (p < 0.05, d = 2.36 (sit-to-stand), d = 2.76 (walk)).

    “In addition, significant improvements were observed in dual-task performance in the HIFE group compared with the control group (p < 0.05). Large effect sizes were observed for the 30-second sit-to-stand test (d = 2.36) and the 4-meter walk test (d = 2.76).”

    Human trialpostmenopausal8 weeksfemalesn = 40

    Effects of a high-intensity functional exercise program on menopausal symptoms, physical performance, and dual-task performance in postmenopausal women: a randomized controlled trial

    BMC women's health

Physical function

upin humans1

1 study
  1. High-intensity functional exercise improves physical function in humans (postmenopausal) (p < 0.05, d = 1.97).

    “The HIFE group demonstrated significantly greater improvements in SPPB total score, including 4-meter walk and chair sit-to-stand performance, compared with the control group (p < 0.05, d = 1.97).”

    Human trialpostmenopausal8 weeksfemalesn = 40

    Effects of a high-intensity functional exercise program on menopausal symptoms, physical performance, and dual-task performance in postmenopausal women: a randomized controlled trial

    BMC women's health

Executive function

no changein humans1

1 study
  1. High-intensity functional exercise showed no clear effect on executive function in humans (people with dementia living in nursing homes) (VF -0.53 (95% CI -1.42 to 0.35, p = 0.241) at 4 months; -0.18 (95% CI -1.09 to 0.74) at 7 months).

    “A 4-month, high-intensity functional exercise program had no superior effects on global cognition or executive function in people with dementia living in nursing homes when compared with an attention control activity.”

    Human trialpeople with dementia living in nursing homes4 months

    Effects of Exercise on Cognitive Function in Older People with Dementia: A Randomized Controlled Trial

    Journal of Alzheimer's disease : JAD

Cognitive function

no changein humans1

1 study
  1. High-intensity functional exercise showed no clear effect on cognitive function in humans (people with dementia living in nursing homes) (MMSE -0.27 (95% CI -1.4 to 0.87, p = 0.644) at 4 months; -1.15 (95% CI -2.32 to 0.03) at 7 months).

    “Linear mixed models showed no between-group effects in mean difference from baseline (95% confidence intervals, CI) at 4 months in MMSE (-0.27; 95% CI -1.4 to 0.87, p = 0.644)”

    Human trialpeople with dementia living in nursing homes4 months

    Effects of Exercise on Cognitive Function in Older People with Dementia: A Randomized Controlled Trial

    Journal of Alzheimer's disease : JAD

Therapist treatment time

downin humans1

1 study
  1. High-intensity functional exercise decreases therapist treatment time in humans (group physiotherapy versus individual physiotherapy alone) (31-205 min/week saved).

    “Therapists saved 31-205 min/week treating group participants compared with control participants”

    Human trialgroup physiotherapy versus individual physiotherapy alonen = 468

    The effects of a high-intensity functional exercise group on clinical outcomes in hospitalised older adults: an assessor-blinded, randomised-controlled trial

    Age and ageing

Discharge destination

no changein humans1

1 study
  1. High-intensity functional exercise showed no clear effect on discharge destination in humans (P = 0.904).

    “no difference in discharge destination, P = 0.904”

    Human trialgroup programme combined with individual physiotherapy versus individual physiotherapy alonen = 468

    The effects of a high-intensity functional exercise group on clinical outcomes in hospitalised older adults: an assessor-blinded, randomised-controlled trial

    Age and ageing

Mobility

no changein humans1

1 study
  1. High-intensity functional exercise showed no clear effect on mobility in humans (effect size -0.07, 95% CI -0.26 to 0.11, P = 0.446).

    “There was no difference between groups for the improvement in EMS from admission to discharge (effect size -0.07, 95% confidence interval: -0.26 to 0.11, P = 0.446)”

    Human trialgroup programme combined with individual physiotherapy versus individual physiotherapy alonen = 468

    The effects of a high-intensity functional exercise group on clinical outcomes in hospitalised older adults: an assessor-blinded, randomised-controlled trial

    Age and ageing

Activities of daily living independence and balance

upin humans1

1 study
  1. High-intensity functional exercise improves activities of daily living independence and balance in humans (participants with non-Alzheimer's dementia).

    “Positive between-group exercise effects were found in participants with non-Alzheimer's dementia according to the FIM at 7 months and BI and BBS at 4 and 7 months.”

    Human trialparticipants with non-Alzheimer's dementia4 months

    Effects of a High-Intensity Functional Exercise Program on Dependence in Activities of Daily Living and Balance in Older Adults with Dementia

    Journal of the American Geriatrics Society

Balance

upin humans1

1 study
  1. High-intensity functional exercise improves balance in humans (older adults with dementia in residential care) (BBS 4.2, 95% CI 1.8 to 6.6).

    “A significant between-group effect on balance favoring exercise was observed at 4 months (BBS=4.2, 95% CI=1.8-6.6).”

    Human trialolder adults with dementia in residential care4 monthsn = 186

    Effects of a High-Intensity Functional Exercise Program on Dependence in Activities of Daily Living and Balance in Older Adults with Dementia

    Journal of the American Geriatrics Society

What is high-intensity functional exercise linked with?

1

Studies link high-intensity functional exercise with 1 measure, most often falls (1 study).

Falls

downin humans1−69% likelihood of moderate and severe falls

1 study
  1. High-intensity functional exercise lowers the risk of falls in humans (nursing homes) (-69% likelihood of moderate and severe falls).

    “Participants in high-intensity functional exercise were 69% less likely to experience moderate and severe (including fractures) falls.”

    Reviewnursing homes

    INTERVENTIONS TO PREVENT FALLS AND FRACTURES IN NURSING HOMES: A SYSTEMIC LITERATURE REVIEW

    Visuomenės sveikata.

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See all 11 papers on high-intensity functional exercise