Healthy macrophages

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Alvin J. Siteman Cancer Center and others
  • Animals1

Outcomes

1

Age-related macular degeneration

downin mice1

1 study
  1. Healthy macrophages decrease age-related macular degeneration in mice.

    “Subretinal administration of healthy macrophages promotes the clearance of senescent macrophages, reversing the AMD disease burden.”

    Animalssubretinal administration

    LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD⁺ depletion

    Cell reports17 Apr 2024

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