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Head injury

Exposure

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Heart, Lung, and Blood Institute and 4 more
  • Humans1

Outcomes

2

Gait speed

downin humans1

1 study

  1. Head injury decreases gait speed in humans (0.02 m/s greater decline (95% CI: -0.04 to -0.01)).

    “Prospectively, head injury was associated with a 0.02 m/s greater decline (95% CI: -0.04 to -0.01) in gait speed over a median of 5 years.”

    Humansmedian of 5 years

    Associations Between Prior Head Injury, Physical Functioning, and Frailty in the Atherosclerosis Risk in Communities Study

    The journals of gerontology. Series A, Biological sciences and medical sciences29 Jan 2024

Physical functioning

downin humans1

1 study

  1. Head injury impairs physical functioning in humans (β-coefficient = -0.22, 95% CI: -0.35 to -0.09).

    “individuals with head injury had worse physical functioning (SPPB total score, β-coefficient = -0.22, 95% CI: -0.35 to -0.09)”

    Humans

    Associations Between Prior Head Injury, Physical Functioning, and Frailty in the Atherosclerosis Risk in Communities Study

    The journals of gerontology. Series A, Biological sciences and medical sciences29 Jan 2024

Associations

1

Frailty

upin humans1OR 1.4

1 study

  1. Head injury raises the risk of frailty in humans (OR = 1.40, 95% CI: 1.08 to 1.80).

    “were more likely to be pre-frail (OR = 1.19, 95% CI: 1.04 to 1.35) or frail (OR = 1.40, 95% CI: 1.08 to 1.80) compared to robust”

    Humans

    Associations Between Prior Head Injury, Physical Functioning, and Frailty in the Atherosclerosis Risk in Communities Study

    The journals of gerontology. Series A, Biological sciences and medical sciences29 Jan 2024

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