Go 6976

  • 1 lab in 1 country
  • Cells1

Outcomes

3

PTHLH

downin human cells1

1 study
  1. Go 6976 decreases PTHLH in human cells.

    “PKC inhibition promoted osteogenic differentiation and inhibits the expression of SOST and Parathyroid hormone-related protein (PTHLH).”

    Cellssenescent human DFCs

    Inhibition of protein kinase C activity enables mineralization of senescent dental follicle cells with almost no osteogenic differentiation potential

    Archives of oral biology2 Dec 2025

More on PTHLH

SOST

downin human cells1

1 study
  1. Go 6976 decreases SOST in human cells.

    “PKC inhibition promoted osteogenic differentiation and inhibits the expression of SOST and Parathyroid hormone-related protein (PTHLH).”

    Cellssenescent human DFCs

    Inhibition of protein kinase C activity enables mineralization of senescent dental follicle cells with almost no osteogenic differentiation potential

    Archives of oral biology2 Dec 2025

More on SOST

Osteogenic differentiation

upin human cells1

1 study
  1. Go 6976 improves osteogenic differentiation in human cells.

    “PKC inhibition promoted osteogenic differentiation and inhibits the expression of SOST and Parathyroid hormone-related protein (PTHLH).”

    Cellssenescent human DFCs

    Inhibition of protein kinase C activity enables mineralization of senescent dental follicle cells with almost no osteogenic differentiation potential

    Archives of oral biology2 Dec 2025

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