Glucose-fed microbiota
Glucose-fed microbiota has been studied in 2 papers since 2023: none in people yet, 2 in animals. The research so far is in animals. The newest paper, Jun 7, 2024: “Glucose-fed microbiota alters C. elegans intestinal epithelium and increases susceptibility to multiple bacterial pathogens”.
2 papers study it10 findingsUpdated
- 1 lab in 1 country
- Funders: Army Research Office and 6 more
- Model organisms2
What did studies of Glucose-fed microbiota find?
7Studies of Glucose-fed microbiota measured 7 outcomes; the most studied are susceptibility to bacterial pathogens (2 studies), locomotion (2) and lifespan (2).
Susceptibility to bacterial pathogens
upin worms2
2 studies
Susceptibility to bacterial pathogens
upin worms2
Glucose-fed microbiota increases susceptibility to bacterial pathogens in worms.
“the changes in the intestinal epithelium due to aging with the glucose-fed microbiota results in increased susceptibility to multiple bacterial pathogens.”
Model organisms
Scientific reports
Glucose-fed microbiota increases susceptibility to bacterial pathogens in worms.
“changes in the intestinal epithelium due to aging with the glucose fed microbiota results in increased susceptibility to multiple bacterial pathogens”
Model organisms
bioRxiv (Cold Spring Harbor Laboratory)Preprint
Locomotion
downin worms2
2 studies
Locomotion
downin worms2
Glucose-fed microbiota impairs locomotion in worms.
“This glucose-fed microbiota results in a significant lifespan reduction accompanied by reduced healthspan (locomotion)”
Model organismsglucose-fed Escherichia coli
Scientific reports
Glucose-fed microbiota impairs locomotion in worms.
“accompanied by reduced healthspan including locomotion, stress resistance, and changes in behavior and feeding”
Model organisms
bioRxiv (Cold Spring Harbor Laboratory)Preprint
Lifespan
downin worms2
2 studies
Lifespan
downin worms2
Glucose-fed microbiota shortens lifespan in worms.
“This glucose-fed microbiota results in a significant lifespan reduction”
Model organismsglucose-fed Escherichia coli
Scientific reports
Glucose-fed microbiota shortens lifespan in worms.
“This glucose-fed microbiota results in a significant lifespan reduction”
Model organisms
bioRxiv (Cold Spring Harbor Laboratory)Preprint
Intestinal cell permeability
upin worms1
1 study
Intestinal cell permeability
upin worms1
Glucose-fed microbiota increases intestinal cell permeability in worms.
“The glucose-fed microbiota accelerated the age-related development of intestinal cell permeability, intestinal distention, and dysregulation of immune effectors.”
Model organismsage-related developmentintestinal epithelium
Scientific reports
Reactive oxygen species
upin worms1
1 study
Reactive oxygen species
upin worms1
Glucose-fed microbiota increases reactive oxygen species in worms.
“Lifespan reduction is also accompanied by two potential major contributors: increased intestinal bacterial density and increased concentration of reactive oxygen species.”
Model organisms
Scientific reports
Intestinal bacterial density
upin worms1
1 study
Intestinal bacterial density
upin worms1
Glucose-fed microbiota increases intestinal bacterial density in worms.
“Lifespan reduction is also accompanied by two potential major contributors: increased intestinal bacterial density and increased concentration of reactive oxygen species.”
Model organismsintestine
Scientific reports
Intestinal permeability
upin worms1
1 study
Intestinal permeability
upin worms1
Glucose-fed microbiota increases intestinal permeability in worms.
“The glucose-fed microbiota accelerated the age-related development of intestinal cell permeability, intestinal distention, and dysregulation of immune effectors.”
Model organismsintestine
bioRxiv (Cold Spring Harbor Laboratory)Preprint