GHRH plus GHRP-6
GHRH plus GHRP-6 has been studied in 2 papers since 1991: 1 trial in people, 1 in animals. The newest paper, Feb 1, 1995: “Growth hormone secretion after the administration of GHRP-6 or GHRH combined with GHRP-6 does not decline in late adulthood”.
2 papers study it2 findingsUpdated
See all 2 papers on GHRH plus GHRP-6
At a glance
The findings reach people, from one lab or study. 2 independent labs in 2 countries.
“the combined administration of GHRH and GHRP-6 elicited a greater GH increase than GHRH alone (F = 21.9, P < 0.001)”
None of its findings points the other way.
- 2 independent labs in 2 countries
- Human trial1
- Animals1
Studies in people
1 study gave GHRH plus GHRP-6 to people and measured what changed.
| What changed | Design | People | Source |
|---|---|---|---|
up: Increases growth hormone secretionF = 21.9, P < 0.001 | Randomized trial | 9 peopleyoung adults (22 ± 1.1 years)Older adults | Clinical endocrinology, Feb 1, 1995 |
What did studies of GHRH plus GHRP-6 find?
2Studies of GHRH plus GHRP-6 measured 2 outcomes; the most studied are growth hormone secretion (1 study) and plasma growth hormone (1).
Growth hormone secretion
upin humans1
1 study
Growth hormone secretion
upin humans1
GHRH plus GHRP-6 increases growth hormone secretion in humans (compared with GHRH alone, in young adults) (F = 21.9, P < 0.001).
“the combined administration of GHRH and GHRP-6 elicited a greater GH increase than GHRH alone (F = 21.9, P < 0.001)”
Human trialcompared with GHRH alone, in young adultsn = 9
Clinical endocrinology
Plasma growth hormone
upin rats1
1 study
Plasma growth hormone
upin rats1
GHRH plus GHRP-6 increases plasma growth hormone in rats (co-administration in old female rats vs young rats) (mean Cmax 8539 +/- 790.6 micrograms/l (old) vs 2970 +/- 866 micrograms/l (young)).
“the increase in plasma GH secretion as a function of time following co-administration of GHRP-6 and GHRH was higher (p less than 0.001) in old rats than in young rats”
Animalsco-administration in old female rats vs young ratsGHRP-6 30 micrograms/kg, GHRH 2 micrograms/kgfemales
Life sciences