Gerontogens

Gerontogens raise the risk of mortality.

“Environmental factors that accelerate biological aging, known as gerontogens, increase organismal vulnerability and susceptibility to disease, thereby elevating the risks of multiple aging-related disease onset and mortality.”

Review

The emerging role of the melatonin-cortisol axis: Bridging aging-related biomarkers to environment-driven aging research

Ageing research reviews·21 Feb 2026