Fructooligosaccharides + soy isoflavones

1 paper5 findings

PubChem 439709 PubChem 70267806 ChEBI 28645

In ovariectomised female rats, fructooligosaccharides plus soy isoflavones improve neurobehaviour and body weight, reduce inflammation, oxidative stress and reactive oxygen species signalling in the hippocampus and colon, and activate hippocampal ESR2. The work comes from one lab, without independent replication or human studies.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Animals1

Outcomes

Inflammation

downin rats1

1 study

Fructooligosaccharides + soy isoflavones decrease inflammation in rats.
Animalsin estrogen-deprived (ovariectomized) ratshippocampus and colonFOS (50 mg/kg) & SIF (40 mg/kg)28 daysfemales
Co-supplementation of fructooligosaccharide with soy isoflavone restores the gut-brain axis dysfunction via modulation of gut microbiome in estrogen-deprived rat model
Molecular biology reports7 Aug 2026

Latest

1 in 12 months

Molecular Biology Reports7 Aug

Co-supplementation of fructooligosaccharide with soy isoflavone restores the gut-brain axis dysfunction via modulation of gut microbiome in estrogen-deprived rat model

Experiments in ratsGut and microbiome

Paper

Fructooligosaccharides + soy isoflavones

Outcomes

Latest

Co-supplementation of fructooligosaccharide with soy isoflavone restores the gut-brain axis dysfunction via modulation of gut microbiome in estrogen-deprived rat model

Related