Four-limb linkage training
Four-limb linkage training has been studied in 1 paper since 2026: 1 trial in people; 1 in the past year. The newest paper, Mar 24, 2026: “A Retrospective Controlled Study on the Effects of Four-Limb Linkage Training on Clinical Efficacy and Antioxidative Mechanisms in Patients with Chronic Obstructive Pulmonary Disease”.
1 paper studies it4 findingsUpdated
“pulmonary function indices, exercise capacity, and quality-of-life scores were significantly improved”
None of its findings points the other way.
- 1 lab in 1 country
- Human trial1
What did studies of Four-limb linkage training find?
4Studies of Four-limb linkage training measured 4 outcomes; the most studied are TXNIP (1 study), lung function (1) and dyspnea (1).
TXNIP
downin humans1
1 study
TXNIP
downin humans1
Four-limb linkage training decreases TXNIP in humans.
“whereas TXNIP mRNA and protein expression levels were significantly decreased at Post 8-week intervention”
Human trialin patients with COPD8 weeks
International journal of chronic obstructive pulmonary disease
Lung function
upin humans1
1 study
Lung function
upin humans1
Four-limb linkage training improves lung function in humans.
“The magnitude of improvement was significantly greater in the four-limb linkage training group than in the control group (P<0.05).”
Human trialin patients with COPD8 weeks
International journal of chronic obstructive pulmonary disease
Dyspnea
downin humans1
1 study
Dyspnea
downin humans1
Four-limb linkage training decreases dyspnea in humans.
“while dyspnea scores and BODE index were significantly reduced in both groups compared with Pre-intervention (P<0.05).”
Human trialin patients with COPD8 weeks
International journal of chronic obstructive pulmonary disease
Exercise capacity
upin humans1
1 study
Exercise capacity
upin humans1
Four-limb linkage training improves exercise capacity in humans.
“pulmonary function indices, exercise capacity, and quality-of-life scores were significantly improved”
Human trialin patients with COPD8 weeks
International journal of chronic obstructive pulmonary disease