Firefighting occupation

1. Firefighting occupation is associated with annualized coronary plaque progression in humans.

   “In the serial-CCTA subset, annualized progression of total plaque volume, calcified plaque, and percent atheroma volume was significantly higher than NATURE-CT.”

   HumansSerial-CCTA subset compared with NATURE-CTcoronary arteryn = 62

   Coronary Plaque Burden and Progression in Los Angeles Firefighters Versus Matched Controls: A Cohort Study

   Journal of occupational and environmental medicine·13 Oct 2026

1. Firefighting occupation is associated with low-density plaque prevalence in humans (31% vs 19%).

   “prevalence of low-density plaque (31% vs 19%), all p ≤ 0.01.”

   HumansLos Angeles Fire Department firefighters compared with matched controlscoronary arteryn = 302

   Coronary Plaque Burden and Progression in Los Angeles Firefighters Versus Matched Controls: A Cohort Study

   Journal of occupational and environmental medicine·13 Oct 2026

More on Low-density plaque prevalence

1. Firefighting occupation is associated with percent atheroma volume in humans (3.5% vs 2.3%).

   “percent atheroma volume (3.5% vs 2.3%), and prevalence of low-density plaque (31% vs 19%), all p ≤ 0.01.”

   HumansLos Angeles Fire Department firefighters compared with matched controlscoronary arteryn = 302

   Coronary Plaque Burden and Progression in Los Angeles Firefighters Versus Matched Controls: A Cohort Study

   Journal of occupational and environmental medicine·13 Oct 2026

More on Percent atheroma volume

1. Firefighting occupation is associated with non-calcified plaque volume in humans (108 vs 73 mm3).

   “The LAFD cohort had significantly higher total plaque volume (138 vs 84 mm3), non-calcified plaque volume (108 vs 73 mm3)”

   HumansLos Angeles Fire Department firefighters compared with matched controlscoronary arteryn = 302

   Coronary Plaque Burden and Progression in Los Angeles Firefighters Versus Matched Controls: A Cohort Study

   Journal of occupational and environmental medicine·13 Oct 2026

More on Non-calcified plaque volume

1. Firefighting occupation is associated with total plaque volume in humans (138 vs 84 mm3).

   “The LAFD cohort had significantly higher total plaque volume (138 vs 84 mm3)”

   HumansLos Angeles Fire Department firefighters compared with matched controlscoronary arteryn = 302

   Coronary Plaque Burden and Progression in Los Angeles Firefighters Versus Matched Controls: A Cohort Study

   Journal of occupational and environmental medicine·13 Oct 2026

More on Total plaque volume